Antoni Ribas Selected Research

Mitogen-Activated Protein Kinase Kinases (MEKs)

1/2021	Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib.
1/2021	Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.
1/2021	Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects.
12/2020	PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma.
10/2020	Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i.
10/2020	Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial.
1/2020	Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials.
1/2020	Survival of patients with advanced metastatic melanoma: The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019.
10/2019	Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses.
8/2019	Publisher Correction: Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma.

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Antoni Ribas Research Topics

Disease

252	Melanoma (Melanoma, Malignant) 06/2022 - 11/2002
212	Neoplasms (Cancer) 01/2022 - 02/2002
23	Disease Progression 01/2021 - 01/2010
16	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2007
8	Inflammation (Inflammations) 01/2022 - 05/2009
8	Exanthema (Rash) 01/2021 - 01/2008
8	Fatigue 01/2019 - 01/2010
7	Brain Neoplasms (Brain Tumor) 01/2021 - 05/2007
7	Fever (Fevers) 01/2019 - 07/2009
6	COVID-19 01/2022 - 11/2020
6	Diarrhea 01/2017 - 06/2007
6	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2015 - 06/2011
5	Prostatic Neoplasms (Prostate Cancer) 12/2020 - 08/2008
4	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 07/2008
4	Nausea 05/2015 - 06/2011
4	Keratoacanthoma 01/2015 - 06/2011
4	Experimental Melanoma 11/2009 - 06/2005
3	Synovial Sarcoma (Synovioma) 01/2022 - 01/2017
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 08/2008
3	Infections 01/2021 - 07/2010
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020 - 06/2015
3	Leukemia 07/2019 - 11/2014
3	Pneumonia (Pneumonitis) 01/2019 - 08/2015
3	Neutropenia 08/2015 - 01/2010
3	Body Weight (Weight, Body) 06/2015 - 07/2013
3	Uveal melanoma 08/2014 - 01/2012
3	Liver Neoplasms (Liver Cancer) 12/2007 - 02/2002
3	Hepatocellular Carcinoma (Hepatoma) 12/2007 - 02/2002
2	Pancreatic Neoplasms (Pancreatic Cancer) 10/2021 - 12/2005
2	Wounds and Injuries (Trauma) 01/2021 - 01/2018

Drug/Important Bio-Agent (IBA)

54	VemurafenibIBA 10/2021 - 04/2010
45	pembrolizumabIBA 06/2022 - 07/2013
42	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 01/2011
38	AntigensIBA 01/2022 - 11/2002
30	IpilimumabIBA 01/2022 - 11/2011
29	Immune Checkpoint InhibitorsIBA 01/2022 - 07/2013
29	dabrafenibIBA 01/2022 - 01/2011
25	trametinibIBA 01/2022 - 02/2013
21	AntibodiesIBA 01/2022 - 08/2006
20	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2003
20	tremelimumabIBA 01/2019 - 12/2005
19	Pharmaceutical PreparationsIBA 01/2021 - 01/2010
18	Peptides (Polypeptides)IBA 12/2020 - 02/2003
18	Monoclonal AntibodiesIBA 04/2016 - 12/2005
16	T-Cell Antigen Receptors (T-Cell Receptor)IBA 07/2019 - 11/2009
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2003
15	cobimetinibIBA 10/2021 - 08/2014
15	VaccinesIBA 01/2021 - 11/2002
14	RNA (Ribonucleic Acid)IBA 01/2022 - 06/2003
14	Neoplasm Antigens (Tumor Antigens)IBA 01/2021 - 06/2003
13	LigandsIBA 01/2021 - 08/2005
12	EpitopesIBA 10/2021 - 03/2003
11	Mitogen-Activated Protein KinasesIBA 12/2020 - 01/2012
11	Dacarbazine (DIC)FDA LinkGeneric 01/2020 - 07/2007
11	HLA-A*02:01 antigenIBA 05/2013 - 03/2003
10	CTLA-4 AntigenIBA 10/2020 - 12/2005
9	NivolumabIBA 01/2022 - 01/2015
9	Phosphotransferases (Kinase)IBA 01/2020 - 08/2011
8	B7-H1 AntigenIBA 01/2022 - 06/2015
8	InterferonsIBA 01/2021 - 06/2009
8	CytokinesIBA 01/2019 - 08/2006
6	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 06/2003
6	Programmed Cell Death 1 ReceptorIBA 10/2021 - 01/2015
6	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2021 - 12/2016
6	Interleukin-2 (IL2)IBA 01/2020 - 09/2007
6	EnzymesIBA 01/2017 - 01/2009
5	Proto-Oncogene Proteins B-rafIBA 01/2016 - 09/2010
5	Monophenol Monooxygenase (Tyrosinase)IBA 05/2011 - 04/2008
4	Chimeric Antigen ReceptorsIBA 11/2021 - 09/2014
4	Interferon-gamma (Interferon, gamma)IBA 10/2021 - 09/2010
4	CateninsIBA 01/2020 - 06/2015
4	Immunoglobulin G (IgG)IBA 01/2019 - 07/2007
4	MART-1 AntigenIBA 01/2018 - 04/2008
4	Small Interfering RNA (siRNA)IBA 08/2014 - 04/2010
4	Temozolomide (Temodar)FDA LinkGeneric 02/2013 - 07/2007
3	spartalizumabIBA 01/2022 - 10/2020
3	Cancer VaccinesIBA 01/2019 - 10/2007
3	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2018 - 07/2012
3	PolymersIBA 01/2018 - 03/2013
3	TAK 733IBA 01/2017 - 04/2012
3	Transcription Factors (Transcription Factor)IBA 02/2015 - 01/2009
3	Dihydrotachysterol (AT 10)IBA 05/2014 - 05/2008
3	PLX 4720IBA 03/2013 - 04/2011
3	Protein Kinases (Protein Kinase)IBA 02/2013 - 04/2010
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 10/2011 - 02/2006
3	alpha-Fetoproteins (alpha-Fetoprotein)IBA 12/2007 - 12/2003
2	Circulating Tumor DNAIBA 01/2022 - 11/2018
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022 - 10/2010
2	Death Domain ReceptorsIBA 01/2022 - 01/2021
2	Interleukin-17 (Interleukin 17)IBA 01/2022 - 05/2009
2	Toll-Like Receptor 9IBA 12/2021 - 10/2018
2	HLA Antigens (Human Leukocyte Antigens)IBA 11/2021 - 12/2020
2	COVID-19 VaccinesIBA 11/2021 - 01/2021
2	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2021

Therapy/Procedure

145	Therapeutics 06/2022 - 08/2004
88	Immunotherapy 06/2022 - 02/2002
16	Drug Therapy (Chemotherapy) 01/2018 - 01/2010
5	Cell- and Tissue-Based Therapy (Cell Therapy) 10/2020 - 01/2014
3	Injections 01/2018 - 08/2004
3	Biological Therapy 11/2014 - 12/2008